Search results for "Gastric mucosal atrophy"

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Gastric plasma biomarkers and Operative Link for Gastritis Assessment gastritis stage

2011

Introduction The Operative Link for Gastritis Assessment (OLGA) staging system has been proposed as a histopathological reporting system of gastric atrophy. Noninvasive methods for indirect evaluation of gastric mucosal atrophy by biomarkers are also being introduced. Objectives To analyze gastric mucosal atrophy by biomarkers, pepsinogen I (PgI), pepsinogen II (PgII), PgI/PgII ratio, fasting gastrin-17 (G-17), stimulated gastrin-17 (sG-17), in relation to OLGA gastritis stage. Patients and methods Gastric biopsies were taken from 269 prospective patients referred for upper endoscopy because of dyspeptic problems and evaluated by two expert pathologists (D.J. and P.S.). Atrophy was assessed…

AdultGastritis AtrophicMalemedicine.medical_specialtyStage iiPlasma biomarkersGastroenterologyHelicobacter InfectionsAtrophyPepsinogen AInternal medicineGastrinsPepsinogen CHumansMedicineProspective StudiesStage (cooking)Prospective cohort studyAgedAged 80 and overHelicobacter pyloriHepatologybusiness.industryGeneral surgeryGastroenterologyMiddle Agedmedicine.diseaseFemaleGastritismedicine.symptombusinessGastric mucosal atrophyReporting systemBiomarkersEuropean Journal of Gastroenterology & Hepatology
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T1078 The Validity of a Biomarker Method for Indirect Detection of Gastric Mucosal Atrophy Versus Standard Histopathology

2008

Background Atrophy of the stomach mucosa is considered to be premalignant lesion for gastric cancer development; easy identification of this condition from a blood-sample would allow identifying the group of individuals at increased risk for cancer development.

medicine.medical_specialtyPathologyHepatologybiologybusiness.industryAtrophic gastritisdigestive oral and skin physiologyGastroenterologymedicine.diseaseGastroenterologyIncreased riskAtrophyPepsinInternal medicinemedicinebiology.proteinBiomarker (medicine)HistopathologyCancer developmentbusinessGastric mucosal atrophyGastroenterology
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